Kikuchi–Fujimoto Disease (KFD)

Why in News?

A 32-year-old man from Visakhapatnam was diagnosed with the rare Kikuchi–Fujimoto Disease (KFD) at KIMS Hospitals, Seethammadhara, after nearly six years of recurrent lymph-node swelling and repeated treatment for suspected tuberculosis (TB).

Key Points

Kikuchi–Fujimoto Disease (KFD), also known as Kikuchi disease or histiocytic necrotising lymphadenitis, is a rare inflammatory disorder affecting the lymph nodes.

The disease can closely resemble tuberculosis and lymphoma, making diagnosis challenging, particularly in regions where TB is common.

KFD predominantly affects young adults and school-age children and is slightly more common among females, although males can also develop the disease.

The most characteristic feature is painful swelling of the lymph nodes (lymphadenopathy), particularly in the neck (cervical lymph nodes).

Other common symptoms may include fever, fatigue and general malaise.

Because its clinical presentation can resemble lymphoma or tuberculosis, appropriate diagnostic evaluation is important to avoid prolonged or inappropriate treatment.

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